China (Mainland)
Diamondsupplier 
Itraconazole CAS NO.84625-61-6
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/P,T/T
- Available Specifications:
- Product Details
Keywords
- ITCZ
- ITR
- 3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-pipera-zinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)
Quick Details
- ProName: Itraconazole
- CasNo: 84625-61-6
- Molecular Formula: C35H38Cl2N8O4
- Appearance: white powder
- Application: For research purpose only
- DeliveryTime: 5-7 workdays after payment
- PackAge: 25kg/drum
- Port: Shanghai/Beijing
- ProductionCapacity: 100 Kilogram/Month
- Purity: 99%
- Storage: Keep in a cool & dry place
- Transportation: normal
- LimitNum: 1 Kilogram
- Related Substances: 99%
- Heavy Metal: ≤10ppm
- Valid Period: 2 years
- Molecular Weight: 705.63
Superiority
Itraconazole is the in stock product in WLP Ingredient Inc.
WLP Ingredient Inc was formerly known as Green Valley Biochemical, which was founded in Hong Kong in 2013 and WLPI was officially registered in 2019. In 2023, it reached a long-term strategic cooperation agreement with a local factory of plant extract. which already got HAHAL,KOSHER,ISO9001,ISO2200,HACCP,cGMP
Now it has developed into a comprehensive enterprise integrating R&D, production and sales. And after years of market accumulation and in response to customer needs, we have close cooperation in various fields and production such as human APIs, veterinary APIs, food additives, feed additives, vitamins, amino acids, etc
In the course of business, our company has always adhered to the principle of integrity first and won the praise of our customers. we hope that in the days to come,we can become your important partner and create a better future together
| Q1:Can i get some samples |
| A:Yes, we can provide 10-20 g sample for your testing, please contact us for more details. |
| Q2:What’s your MOQ |
| A:Our MOQ is 1kg. (Packed in aluminum foil bag) |
| Q3:How can I Buy |
| A:Proforma invoice will be sent first after confirmation of your purchase order,enclosed our bank information.Payment by T/T,L/C, or Paypal. |
| Q4:How can you confirm your quality If problem happens,how you treat with your client |
| A:You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and to get the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests. |
| Q5:How do you treat with quality complaint |
| All of products are strictly tested by our QC, and confirmed by QA. We do test for products to make sure all of them are qualified. In case any quality problem is confirmed to be caused by us,we will replace the goods or refund your payment immediately. |
| Q6:What's the delievry time |
| A:Usually 3 working days for small orders,and large orders need to be checked based on different products. |
Details
Itraconazole is an artificially synthetic clotrimazole, being a broad-spectrum synthetic antifungal agent. Its antimicrobial spectrum and antimicrobial mechanism is similar to clotrimazole, but has strong antibacterial activity against Aspergillus.
It exerts its anti-fungal effect through changing the fungal cell membrane permeability with antibacterial activity against superficial and deep fungal pathogens. Its antibacterial spectrum is broader and stronger than ketoconazole, being able to inhibit the ergosterol synthesis of fungal cell membrane, thus playing the antifungal effect.
This product is suitable for the treatment of Dermatophytes (Trichophyton, Microsporum, Flocculent Epidermophyton), Yeast [Cryptococcus neoformans, Pityrosporum, Candida (including Candida albicans, Candida glabrata and candida krusei)], Aspergillus, Histoplasma, Paracoccidioides brasiliensis, Sporothrix schenckii, Hormodendrum, Cladosporium, Blastomyces dermatitidis and various kinds of other types of yeasts and fungi. Itraconazole is not able to inhibit the growth of Rhizopus and Mucor.
| Product Name: | Itraconazole |
| CAS No. | 84625-61-6 |
| Formula: | C16H16N2O3S |
| Melting Point | 238-239 °C |
| Apperance: | Powder |
| Color: | White |
1) Itraconazole has a broader spectrum of activity than fluconazole (but not as broad as voriconazole or posaconazole). In particular, it is active against Aspergillus which fluconazole is not.
2) It is also prescribed for systemic infections, such as aspergillosis, candidiasis, and cryptococcosis
3) Itraconazole has also recently been explored as an anticancer agent for patients with basal cell carcinoma.
The im idazole antifungal agents for the triazole ring, through inhibiting the activation of cytochrome P-450, including oxidase and peroxidase, disable the 14, alpha-methyl sterols to be dehydrogenated and be converted to ergosterol, so that the growth and proliferation of fungi are inhibited. They have strong lipophilicity and penetrate through the biofilm to inhibit the binding of the membrane to the fungus.
The antibacterial spectrum is similar to ketoconazole. It is effective in the treatment of superficial fungal diseases such as vaginal and oral candidiasis as well as skin mycosis. Furthermore, it is expected to become the highly-efficient and safe drugs for the treatment of deep fungal infections such as cryptococcal encephalitis (AIDS). It is used for the treatment of vulvovaginal candidiasis, pityriasis and skin fungal disease pityriasis caused by sensitive fungi.
It can be used for the synthesis of broad-spectrum a zole antifungal agents for the treatment of systemic infection caused by deep fungus. It can also be used for the treatment of candidiasis and aspergillosis.
It is used for the treatment of the following fungal infections in immunocompromised and non-immunocompromised patients: pulmonary and extrapulmonary blastomycosis, histoplasmosis, aspergillosis, and onychomycosis.
It is anti Fungal and used in the treatment of stomach upset/ indigestion and other gastrointestinal conditions.
