- Product Details
Keywords
- Isotretinoin [USAN:BAN:INN]
- (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoate
- Retinoic acid, (13cis)-
Quick Details
- ProName: Isotretinoin
- CasNo: 4759-48-2
- Molecular Formula: C20H28O2
- Appearance: yellow crystalline powder
- Application: Pharmaceutical
- DeliveryTime: 5-7 workdays after payment
- PackAge: 25kg/drum
- Port: Shanghai/Beijing
- ProductionCapacity: 100 Metric Ton/Month
- Purity: 99%
- Storage: Cool and dry place
- Transportation: normal
- LimitNum: 25 Kilogram
- Related Substances: 99%
- Valid Period: 2 years
- Molecular Weight: 268.28
Superiority
Lsotretinoin is the in stock product in WLP Ingredient Inc.
WLP Ingredient Inc was formerly known as Green Valley Biochemical, which was founded in Hong Kong in 2013 and WLPI was officially registered in 2019. In 2023, it reached a long-term strategic cooperation agreement with a local factory of plant extract. which already got HAHAL,KOSHER,ISO9001,ISO2200,HACCP,cGMP
Now it has developed into a comprehensive enterprise integrating R&D, production and sales. And after years of market accumulation and in response to customer needs, we have close cooperation in various fields and production such as human APIs, veterinary APIs, food additives, feed additives, vitamins, amino acids, etc
In the course of business, our company has always adhered to the principle of integrity first and won the praise of our customers. we hope that in the days to come,we can become your important partner and create a better future together
Q1:Can i get some samples |
A:Yes, we can provide 10-20 g sample for your testing, please contact us for more details. |
Q2:What’s your MOQ |
A:Our MOQ is 1kg. (Packed in aluminum foil bag) |
Q3:How can I Buy |
A:Proforma invoice will be sent first after confirmation of your purchase order,enclosed our bank information.Payment by T/T,L/C, or Paypal. |
Q4:How can you confirm your quality If problem happens,how you treat with your client |
A:You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and to get the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests. |
Q5:How do you treat with quality complaint |
All of products are strictly tested by our QC, and confirmed by QA. We do test for products to make sure all of them are qualified. In case any quality problem is confirmed to be caused by us,we will replace the goods or refund your payment immediately. |
Q6:What's the delievry time |
A:Usually 3 working days for small orders,and large orders need to be checked based on different products. |
Details
lsoretinoic acid belongs to the first generation of vitamin A acids. It is a stereoisomer of all trans vitamin A acid. Oral administration has an anti oil effect and has a special effect on severe acne. It has a strong and rapid function of inhibiting the proliferation and differentiation process of skin gland cells. Clinically used for severe acne, cystic acne, and aggregated acne that are ineffective in the treatment of other drugs.
Product Name: | Isotretinoic |
CAS No. | 4759-48-2 |
Formula: | C20h28o2 |
Purity | 99% |
Apperance: | Powder |
Color: | Yellow |
Shelf Life | 2 Years |
Storage: | Store Cool Dry Place |
Formula Weight: | 300.44 |
1. It can reduce sebaceous gland and inhibit the activity of sebaceous gland, reducing the effect of secretion of the sebaceous glands, thus inhibiting the growth of Propionibacterium which relies on lipid environment.
2. It has an anti-keratosis effect, can inhibit the excess proliferation of epidermal and promote its differentiation. It also reduces the keratosis of hair follicles and the catheter of sebaceous glands.
3. It can also affect the function of lymphocytes and monocytes, and inhibit the chemotaxis of neutrophil, and thus having anti-inflammatory activity.
4. It can exert its therapeutic effect by selectively binding Vitamin A acid nuclear receptors. It can inhibit the proliferation of acne rod bacilli. Moreover it has effects of immunity stimulation at low doses, but has immunity suppression effect at high doses.
5. It can inhibit the biogenesis of collagenase and gelatinase in the skin, and can also inhibit the activity of ornithine decarboxylase. Owing to the major role of ornithine decarboxylase in inducing skin mutations, so Isoretinoic can also suppress tumorigenesis.
6. When subjects to topical administration, it has a similar mechanism of action as vitamin A acid which induces the proliferation of epidermal cell, promotes the differentiation of epidermal cell granular layer into the stratum corneum. It can also regulate the horny plug occurring during some abnormal cornification processes of Hair follicle sebaceous epithelium, and thus playing a therapeutic role